Dr Manish Tripathi

Kidney Disease: Causes, Symptoms, and Treatment

What Is Kidney Disease?

Kidney disease means your kidneys — those two bean-shaped organs in your lower back — aren’t working as well as they should. Sometimes, the problem comes on suddenly. Other times, it’s a slow, silent process that takes years before symptoms show up.
The word “disease” may sound scary, but think of it as a spectrum. It can range from mild kidney damage that’s manageable with lifestyle changes to more serious stages where dialysis or even a transplant may be needed. But no matter where you are on that spectrum, there’s help and hope.

What Do the Kidneys Actually Do?

Here’s a simple way to understand it: imagine your body is a city, and your kidneys are the sanitation workers. Every day, they remove trash (toxins), manage water and salt (like plumbing), and keep things running smoothly.
They filter about 50 gallons of blood every single day. They make hormones that regulate your blood pressure. They help produce red blood cells. They even help your bones absorb calcium.
So when your kidneys aren’t functioning properly, it affects almost every other part of your body. That’s why we pay such close attention to them.

Types of Kidney Disease

Kidney disease isn’t just one thing — it’s an umbrella term for several conditions. Here are a few types you might hear about:

Chronic Kidney Disease (CKD)

This is the most common type. It means there’s a gradual loss of kidney function over time. Often, CKD doesn’t cause symptoms until it’s fairly advanced, which is why regular checkups are so important.

Acute Kidney Injury (AKI)

This happens suddenly, often within hours or days. It might be caused by an illness, dehydration, infection, or medications. The good news? AKI can often be reversed with timely treatment.

Polycystic Kidney Disease (PKD)

This is a genetic condition where fluid-filled cysts grow inside the kidneys, sometimes causing them to enlarge or fail.

Glomerulonephritis

A condition that affects the glomeruli, the tiny filters in your kidneys. It can happen on its own or be part of other illnesses like lupus.

What Causes Kidney Disease?

Many people are surprised that kidney disease doesn’t usually start in the kidneys themselves. It’s often a result of other conditions that slowly damage the kidneys over time.

Diabetes

This is the number one cause of kidney disease. High blood sugar can damage the small blood vessels in the kidneys, making it harder for them to filter your blood properly. Over time, this leads to what’s called diabetic nephropathy . It doesn’t happen overnight, but the damage is real and often silent in the early stages.
If you’re living with diabetes, controlling your blood sugar isn’t just about avoiding sugar — it’s about protecting your kidneys, heart, eyes, and nerves too.

High Blood Pressure

Right behind diabetes, high blood pressure (or hypertension) is the second most common cause of kidney disease. Think of your kidneys’ filters like tiny, delicate strainers. When blood pressure is constantly high, it creates a strong force against those tiny filters, leading to wear and tear.
That’s why keeping your blood pressure in check isn’t just about avoiding heart disease or stroke — it’s also critical for kidney health.

Infections, Medications, and Autoimmune Diseases

Sometimes, kidney problems can be triggered by infections like urinary tract infections (UTIs) that move up into the kidneys (called pyelonephritis). Repeated or untreated infections can leave scarring.
Long-term use of certain medications, especially over-the-counter painkillers like ibuprofen, naproxen, or even some antibiotics, can also harm the kidneys if not used carefully. That’s why it’s important to never self-medicate without talking to a doctor, especially if you have existing kidney concerns.
Then there are autoimmune diseases like lupus , where your own immune system attacks your kidneys, causing inflammation and damage. It’s known as lupus nephritis, and it requires specialized treatment to prevent long-term kidney decline.

Other Causes

There are many other possible triggers, too — genetic conditions like polycystic kidney disease, prolonged dehydration, kidney stones, or even heavy metal exposure in rare cases. Sometimes, there’s no clear cause, and we call it idiopathic (which just means “of unknown cause”).
The important thing is to catch kidney disease early, regardless of the cause, because early treatment can make a huge difference.

How Does Alcohol Affect the Kidneys?

You might be wondering, “Is drinking alcohol bad for my kidneys?” It depends on how much and how often. In small amounts, alcohol may not cause direct harm to healthy kidneys. But excessive drinking can lead to dehydration, high blood pressure, and liver disease — all of which make your kidneys work harder.
If you already have kidney issues, even moderate drinking can worsen things. It’s always best to check with your doctor.

Symptoms of Kidney Disease

The tricky part? In the early stages, kidney disease often doesn’t show obvious symptoms. That’s why it’s called a “silent” disease. But as it progresses, you might notice:
For a deeper dive into these warning signs, check out our follow-up guide:

How Do We Diagnose Kidney Disease?

Diagnosing kidney disease is usually straightforward and painless. It typically involves:
These tests help us not only diagnose kidney disease but also track how it’s progressing.

How Do We Treat Kidney Disease?

The right treatment depends on the type and stage of kidney disease, but here’s a broad overview:

Early Stages

Advanced Stages

Most importantly, early intervention can slow or even stop the progression of kidney disease. That’s why catching it early is key.

Frequently Asked Questions (FAQs)

1. Is kidney disease curable?

A: Some types, like acute kidney injury, can be reversed. Chronic kidney disease is usually not curable, but we can manage it well and slow its progression.

2. Can I live with one kidney?

A: Absolutely. Many people live full lives with just one functioning kidney.

3. Should I be worried if I have foamy urine?

A: It can be a sign of protein in the urine, which may point to kidney problems. It’s worth discussing with your doctor.

4. What should I eat if I have kidney disease?

A: A kidney-friendly diet usually means less salt, potassium, and phosphorus. A dietitian can tailor this to your needs.

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